Emerging techniques in molecular detection of circulating tumor cells
نویسندگان
چکیده
منابع مشابه
Detection of Circulating Tumor Cells
The increasing number of treatment options for patients with metastatic carcinomas has created an accompanying need for methods to determine if the tumor will be responsive to the intended therapy and to monitor its effectiveness. Ideally, these methods would be noninvasive and provide quantitative real-time analysis of tumor activity in a variety of carcinomas. Assessment of circulating tumor ...
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Widespread studies on tumor diagnosis has led to the development of techniques with greater sensitivity and improved specificity for detection of occult and small subclinical tumors. Tumor imaging by radiolabeling of tumor-specific antibodies (Immunoscintigraphy) or tissue specific biochemical agents (Receptor imaging) and especially physiologic imaging with positron emitters (PET), have ...
متن کاملMolecular Biomarker Analyses Using Circulating Tumor Cells
BACKGROUND Evaluation of cancer biomarkers from blood could significantly enable biomarker assessment by providing a relatively non-invasive source of representative tumor material. Circulating Tumor Cells (CTCs) isolated from blood of metastatic cancer patients hold significant promise in this regard. METHODOLOGY/PRINCIPAL FINDINGS Using spiked tumor-cells we evaluated CTC capture on differe...
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Here is a dream: find and destroy every tumorous cell in the body, especially those that get into the blood and mercilessly rove for other sites to inhabit. Some scientists in the field of circulating tumor cell (CTC) research feel we are closer to realizing this dream than ever before. The first CTC was identified in 1869. Dr. Peter Kuhn, a professor of biology at the University of Southern Ca...
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PURPOSE Gastric cancer studies indicated a potential correlation between circulating tumor cells (CTCs) in peripheral blood and tumor relapse/metastasis. The prevalence and significance of circulating tumor microemboli (CTM) in gastric cancer remain unknown. We investigated the prevalence and prognostic value of CTCs and CTM for progression-free survival (PFS) and overall survival (OS) in gastr...
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ژورنال
عنوان ژورنال: Expert Review of Molecular Diagnostics
سال: 2014
ISSN: 1473-7159,1744-8352
DOI: 10.1586/14737159.2014.868308